Four baby turtles come in contact with a mysterious substance called ooze and then are transformed into human sized crime fighters. The leader of the turtles is a human size rat who has come into contact with the same green ooze. The rat was a former pet of a ninja master and therefore uses his skills to train the four turtles in martial arts. They befriend a local journalist and with her help attempt to find the group behind a crime wave in New York City.
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