Raja Rani is about John, a young man, and Regina, a woman, who get married, even though they can't stand each other and how they realize that, there is life and love in their new relationship. Both have a romantic past - she with the innocent Jai and he with the chirpy Nazriya - have lost their loved ones in different ways, and are unwilling to come out of their loss. How they decide to let go of the past and embrace the future is what the plot is all about.