Damián, Facundo, Luciano and Marcelo are 4 best friends who share a deep affection for music. They also happen to be crossing a midlife crisis, regarding their women and jobs. Damián is a screenwriter who’s writing a new and serious script based on his last relationship with a snobby art critic. Facundo, despite being the ladies man, is getting married. Luciano is a neurotic radio host whose jealousy and eventual break-up with a hot wannabe singer leaves him deaf. Marcelo has his 20 years old Beatles-tribute band called The Hitles, and reality will overshadow history when a Colombian-Asian woman, whose initials are those of Yoko Ono, comes to share his apartment.