Mayor Tom Kane (Golden Globe Winner Kelsey Grammer) is King of Chicago and he rules his domain with an iron fist. Deception, scandal, and betrayal go hand in hand with Kane's form of politics. As long as he gets the job done, the people of Chicago look the other way. Despite being the most effective mayor in recent history, Kane is hiding a dark secret. A degenerative brain disorder is ripping everything away from him and he can't trust his memory, his closest allies, or even himself.
After the discovery of a serious medical condition, Mayor Tom Kane must set things in motion for the upcoming gubernatorial primary while attempting to reconnect with his distant wife and estranged daughter.