Based on the best-selling crime novels, Angie Harmon and Sasha Alexander star as detective Jane Rizzoli and medical examiner Maura Isles. Opposites in many ways — Rizzoli is brash and tomboyish; the methodical and impeccably dressed Isles is often icy — together, they use their brilliant minds to bust Boston's most notorious criminals.
The virtual world and the real world collide when a microbrewer is killed. Angela tries to move on from a failed romance by seeing someone new. And Jane and the team begin to mentor underprivileged teenagers, a move that ends in near disaster.