A maverick toymaker who never knew he invented a billion-dollar brick. A designer who put a smile on the face of the world for just $45. A child of slaves whose hair loss cure spurred her to make millions. And an engineer whose brilliant innovation led to a 30-year legal nightmare that drove him to the brink of bankruptcy and madness. We celebrate the little guys whose big ideas led to revolutionary inventions and pop-cultural phenomena, as well as dramatic and shocking events, good and bad, that would change their lives forever.