As the purged Cardinals are dismissed and stripped of their titles and wealth, one of them - Cardinal Versucci (Vernon Dobtcheff) - angrily sets the Vatican Treasury ablaze after stealing a large sum. Incensed by the new King Ferdinand's (Matias Varela) arrogant refusal to accept Giovanni as Lucrezia's (Holliday Grainger) child, Cesare (Francois Arnaud) travels to Naples to fix the problem. Later, Cesare begins to consider an alliance with the old enemy France while Alexander doggedly sticks to his plan of allying with Naples, and therefore, Spain. After Lucrezia and Alfonso's wedding, Alfonso (Sebastian De Souza) realizes that the political sands are shifting - and not in his favour. Upset, he leaves Lucrezia alone on her wedding night, driving her into the arms of her own brother at last.