List of human genes

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Mayelana nalolu hlelo lokusebenza

I-genome yomuntu iqoqo eliphelele lokulandelana kwe-nucleic acid kubantu, okufakwe njenge-DNA ngaphakathi kwamabili angama-23 e-chromosome ku-cell nuclei naku-molecule encane ye-DNA etholakala ngaphakathi kwe-mitochondria ngayinye. Ama-genomes womuntu afaka phakathi zombili izakhi zofuzo ze-DNA kanye ne-noncoding DNA. Ama-genome womuntu athambile, atholakala kumaseli wamagciwane (amaqanda nesidoda gamete amangqamuzana adalwe esigabeni se-meiosis sokukhiqiza kabusha ngokocansi ngaphambi kokukhulelwa kukhiqize i-zygote) aqukethe ama-base ayisisekelo ayizigidi ezintathu ze-DNA, kanti ama-diploid genomes (atholakala kumaseli we-somatic) anezikhathi eziphindwe kabili okuqukethwe kwe-DNA. Ngenkathi kukhona umehluko ophawulekayo phakathi kwama-genome abantu (ngokulandelana kuka-0.1%), [1] lokhu kuncane kakhulu kunokwehluka phakathi kwabantu nezihlobo zabo eziseduze kakhulu, izimfene (cishe u-4% [2]) nama-bonobos . Nalu uhlu lwezakhi zofuzo zomuntu ezihlukaniswe nge-chromosome.