Labinsane

Carlos Poblete Jara

About this app

This tool helps researchers and veterinarians to calculate doses of analgesic, anesthetic and streptosotozin. Labinsane calculates intraperitoneal dose of streptozotocin for induction of diabetes in mice with a single dose (1). In addition, a formula is added to calculate the dose for anesthesia induction in C57 and Swiss micen (2), in order to reduce the risk of applying a higher or lower dose of these medicines and thus save time, animals and limited resources.



1= Arora S, Ojha SK, Vohora D. Characterisation of streptozotocin induced diabetes mellitus in swiss albino mice. Global J Pharmacol. 2009;3(2):81-4.
2= Jaber SM, Hankenson FC, Heng K, McKinstry-Wu A, Kelz MB, Marx JO. Dose Regimens, Variability, and Complications Associated with Using Repeat-Bolus Dosing to Extend a Surgical Plane of Anesthesia in Laboratory Mice. Journal of the American Association for Laboratory Animal Science : JAALAS. 2014;53(6):684-91