Pathogenesis Sim

Gaige

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About this game

Unleash your pathogen and rewrite human history. Pathogenesis Sim is a deep, strategic outbreak simulator where every decision shapes the fate of the world. Evolve transmission traits, adapt to global climates, outsmart international healthcare systems, and spread your disease across every continent before humanity fights back.

Track real‑time infection data, monitor country‑by‑country stats, and choose your evolutionary path: stealthy spreader, aggressive killer, or unstoppable hybrid. With dynamic world events, adaptive AI responses, and multiple ways to win, no two runs are ever the same.

Features

Global simulation with evolving world conditions

Transmission, symptom, and ability evolution trees

Country‑level stats: climate, wealth, healthcare, borders

Dynamic events that change strategy mid‑game

Multiple difficulty modes and progression profile

Replayable runs with unique outcomes

Can your pathogen take over the world before the cure is complete?

What’s new

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