This much praised and widely used reference manual on has been extensively revised and expanded to cover the entire field of anatomic pathology. The Third Edition features the incorporation of full-color images in the text with updates of new diagnostic and prognostic information. New classifications and numerous new entities and histologic variants are fully explored. Useful immunostaining biomarkers and emerging molecular targets and relevant molecular findings that have emerged from recent genomic studies are incorporated in each chapter.
Written by internationally recognized authorities, the comprehensive, evidence-based practice information is presented in an outline format that is clear and easy to follow. Up-to-date and richly detailed, Essentials of Anatomic Pathology, Third Edition offers both the pathologist-in-training and the practicing pathologist a concise summary of all the critical information needed to recognize, understand and interpret anatomic pathology.
"DOCTOR RAT is dazzlingly original, witty and insanely satiric. It is also occasionally quite beautiful. Kotzwinkle's tale is a dizzying montage...from scenes of gross black humor in the experimental lab to idyllic glimpses of the animal kingdom. Designed to shock us into ecological awareness, Kotzwinkle's lab experiments are hair-raising."
--Los Angeles Times
A bloodcurdling novel in the spirit of ANIMAL FARM and 1984, DOCTOR RAT is a trip through a laboratory worthy of a Nazi mad doctor, except this doctor is a wisecracking rodent who could have been played by Groucho Marx. The London Times called DOCTOR RAT, "a splendidly nutty animal Magnificat with echoes of William Blake."
"Mr. Kotzwinkle is a first-rate fabulist."
--The New York Times
Inspired by the need for a user-friendly chemical engineering text that demonstrates the real-world applicability of different computer programs, Introduction to Software for Chemical Engineers acquaints readers with the capabilities of various general purpose, mathematical, process modeling and simulation, optimization, and specialized software packages, while explaining how to use the software to solve typical problems in fluid mechanics, heat and mass transfer, mass and energy balances, unit operations, reactor engineering, and process and equipment design and control.
Employing nitric acid production, methanol and ammonia recycle loops, and SO2 oxidation reactor case studies and other practical examples, Introduction to Software for Chemical Engineers shows how computer packages such as Excel, MATLAB®, Mathcad, CHEMCAD, Aspen HYSYS®, gPROMS, CFD, DEM, GAMS, and AIMMS are used in the design and operation of chemical reactors, distillation columns, cooling towers, and more.
Make Introduction to Software for Chemical Engineers your go-to guide and quick reference for the use of computer software in chemical engineering applications.
With over 20 easy-to-use template protocols for cleaning validation of extensively used equipments, this book provides technical solutions to assist in fulfilling the training needs of finished pharmaceutical manufacturers. Drawing on the authors’ more than two decades of experience in the pharmaceutical and biotech industries, the text offers hands-on training based on current approaches and techniques. The book does not merely provide guidelines or thought processes, rather it gives ready-to-use formulas to develop Master Plan, SOPs, and validation protocols. It includes cleaning procedures for the most commonly used equipment in various manufacturing areas and their sampling points, using a pharmaceutical manufacturing site with both sterile and non-sterile operations as the case facility. It also provides the training guidelines on a CD-ROM to enable users to amend or adopt them as necessary.
Grounded in practicality, the book’s applicability and accessibility set it apart. It can be used as a guide for implementing a cleaning validation program on site without the help of external consultants, making it a resource that will not be found collecting dust on a shelf, but rather, referred to again and again.
The chapters cover: quantitative methods (proteins, nucleic acids, phospholipids and carbohydrates), electrophoresis (several polyacrylamide and agarose systems, 2D-PAGE, detection methods and affinity electrophoresis), chromatographic protocols (thin-layer chromatography, GPC, IEC, affinity chromatography, HPLC), immunochemical protocols (hapten-carrier and enzyme conjugation, immunization and antibody purification, immune affinity chromatography, ELISA), centrifugation (differential and density gradient centrifugation for cells and cellular fractions), radioactivity (labeling and counting), buffers (buffer properties and compositions).
In additional chapters, tables compile a broad array of useful information, e.g. SI units conversion factor, detergent, protein and nucleotide data, and the basic principles of statistics and enzyme and receptor kinetics are reviewed.
This first English-language edition of a successful German-language manual will be a valuable resource for students and experts in biochemistry, biotechnology and biomedical laboratories.
Comprised of four concise and comprehensive chapters, the book presents stepwise procedures for sectioning of plant material, histo-chemical staining techniques, and the anatomy of forty well-known and medicinally important plants, including Arjuna, Ashoka, Ashwagandha, Cinchona, Cinnamon, Ginger, Kurchi, Rauwolfia, Turmeric, Tulsi, and Vasaka. The book is also supplemented with color photographs and hand-drawn microscopic images.
Written by authorities in the field, Indian Herbal Drug Microscopy is a valuable guide for herbal drug microscopy of Indian medicinal plants.
* Cross-referenced throughout for easy comprehension
* Superbly illustrated with over 700 photos, drawings, and diagrams, including 36 color plates
* Provides 40 thematically organized chapters by more than 50 eminent contributors
* Convenient glossaries of technical terms introduce each chapter
* Academic Press maintains a web site for the Encyclopedia at www.academicpress.com/solar; Author-recommended web resources for additional information, images, and research developments related to each chapter of this volume, are available here
It begins with an introduction to clinical computing and definition of key terminology. The next several chapters talk about system architecture and interface design, followed by detailed discussion of all aspects of operations. Attention is then given to the realities of leadership, planning, oversight, budgeting, and employee recruitment. This invaluable resource includes a special section that talks about career development for students and others interested in entering the field.
*Provides a complete overview of practical aspects
*Detailed guidance on the design and operation of clinical computing systems
*Discusses how clinical computing systems relate to health care organization committees and organizational structure
*Includes numerous real-life examples with expert insights on how to avoid pitfalls
--David M. Schneider, The University of Chicago
The book also contains thorough discussions of the principles underlying all spectroscopic instrumentation, with special emphasis on grating instruments used with telescopes. An introduction to adaptive optics provides the needed background for further inquiry into this rapidly developing area.Geometrical aberration theory based on Fermat's principleDiffraction theory and transfer function approach to near-perfect telescopesThorough discussion of 2-mirror telescopes, including misalignmentsBasic principles of spectrometry; grating and echelle instrumentsSchmidt and other catadioptric telescopesPrinciples of adaptive opticsOver 220 figures and nearly 90 summary tables
Modern Cosmology is the first book to explain in detail the structure of the acoustic peaks in the CMB, the E/B decomposition in polarization which may allow for detection of primordial gravity waves, and the modern analysis techniques used on increasingly large cosmological data sets. Readers will gain the tools needed to work in cosmology and learn how modern observations are rapidly revolutionizing our picture of the universe.Provides foundations, calculations, and interpretations which illuminate current thinking in cosmologyCovers the major advances in cosmology over the past decadeIncludes over 100 unique, pedagogical figures
Contains several real world examples of problems in preclinical studies to provide you with an idea of the types of challenges that are routinely encountered and how this book can help you avoid these issues.
Provides monitoring checklists through the book that will help you comply with each GLP requirement and maintain compliance throughout the entire process.
Both entry level and experienced scientists involved in nonclinical toxicology study monitoring will benefit from the ideas, examples, discussions and strategies presented throughout this book.
Erroneous hospital and pathology laboratory results can be confusing and problematic, especially in acute care situations. While some factors creating interference, can be identified in the laboratory, detecting many others is often dependent on clinical details unavailable to the laboratory scientists or pathologists. Therefore, clinicians must become proficient in identifying such erroneous reports, and working with pathologists and laboratory scientists so that they can understand the source of such interferences, correct the results, and then decide what course of action must be followed for proper patient management.Named to Doody’s Core Titles 2013, a collection development tool for health sciences libraries of all sizes, by Doody EnterprisesPractical information for both clinicians and laboratory scientists, presented in the form of tables and charts for easy referenceFocus on range and sources of interferences rather than details of toxicologic mechanisms which are well covered in toxicology textbooksCovers interferences across endocrine, oncology, hematology, immunohistochemistry, immunology, serology, microbiology, and molecular testing
Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of much referenced mouse resources, The Guide to Investigation of Mouse Pregnancy is the only manual providing needed content on pregnancy in animal models for translational medicine and research.Provides instruction on how to collect pre-clinical data on pregnancy in mouse models for eventual use in human applicationsDescribes the angiogenic tree the mother’s uterus develops to support pregnancy and the monitoring of pregnancy-induced cardiovascular changesEducates readers on placental cell lineages, decidual development including immune cells, epigenetic regulation, gene imprinting, stem cells, birth and lactationDiscusses how stress, environmental toxicants and other manipulations impact upon placental function and pregnancy success