Supplying insight from international experts, this guide
Discusses formulation for poorly soluble drugs Presents biological requirements for nanotherapeutic applications Demonstrates the role of nanobiotechnology in the development of nanomedicine Documents recent advances in nanoparticulate technology—including electrospining, formation of microcrystals, and production of liquid crystalline phases Examines the technology of metallic nanoparticles
Building a foundation with coverage of historical background, definitions, and challenges, the book offers insight into nutraceutical ingredients from plant, animal, and mineral origin. It then covers the characterization of nutraceuticals’ physicochemical, analytical, pharmacological, and pharmacokinetic classification, followed by information on regulatory requirements. The book highlights applications in cardiovascular disease, bone and joint treatments, diabetes management, weight management, skin health, probiotics and prebiotics, tranquilizing medicinal plants, dietary foods, and more.
Interest in new diet regimens and new products for increased health and longevity will continue to grow, giving dietary supplements an increasing amount of cupboard space in most households. With quality of content unsurpassed by many resources, the book discusses the characterization processes for nutraceuticals based on the contributors’ experience in pharmaceuticals. It then explores how those proven techniques may be applied to the development and manufacture of nutraceutical products.
The first volume of the Handbook of Nutraceuticals re-defined Nutraceuticals, covering the regulatory aspect as well as insisting on the cGMP’s and SOP’s for the nutraceutical manufacturing. This second volume focuses on the scale up, processing, and automation of nutraceutical production under cGMP production regulations. It covers:
Advancements in extraction methods Unit operations involved in scaling up and processing Rheological and flow properties of products as characterization parameters Fortification and value enhancement using nanotechnology Green concepts in food industry Flavoring of nutraceuticals Clinical batch nutraceutical manufacturing New technologies to prevent counterfeiting Automation in nutraceutical industry
The nutraceutical market is at the crossroads. With a nearly $200 billion market for nutraceuticals and functional foods by end of 2013, and promising developments in product design and discovery, the industry must be ready for intense scrutiny. The standardization of testing, clinical studies, and adherence to rigorous industry and scientific methods is necessary for the advancement, acceptance, and development of high quality, effective nutraceuticals. With contributions from leading authorities, this book brings together hundreds of years of combined experience to provide guidance on how to increase the quality and credibility of nutraceutical products.
For more than three decades, millions of consumers have trusted The Pill Book to provide official, FDA-approved information on more than 1,800 of the most commonly prescribed drugs in the United States with guidelines from leading pharmacists. Each drug is profiled in a concise, readable, easy-to-understand entry, making The Pill Book the perfect reference when you have questions about the medications your doctor prescribes. Inside you’ll discover
• generic and brand-name listings that can help you save money
• What each drug is for, and how it works
• usual dosages, and what to do if a dose is skipped
• side effects and possible adverse reactions, highlighted for quick reference
• interactions with other drugs and food
• overdose and addiction potential
• alcohol-free and sugar-free medications
• the most popular self-injected medications and their safe handling
• information for seniors, pregnant and breast-feeding women, children, and others with special needs
• cautions and warnings, and when to call your doctor
• 32 pages of actual-size color photographs of prescription pills*
No home should be without this book!
*Not all ereading devices will show the images in color and at the exact size.
Today’s optimistic farm-to-table food culture has a dark secret: the local food movement has failed to change how we eat. It has also offered a false promise for the future of food. In his visionary New York Times–bestselling book, chef Dan Barber, recently showcased on Netflix’s Chef’s Table, offers a radical new way of thinking about food that will heal the land and taste good, too. Looking to the detrimental cooking of our past, and the misguided dining of our present, Barber points to a future “third plate”: a new form of American eating where good farming and good food intersect. Barber’s The Third Plate charts a bright path forward for eaters and chefs alike, daring everyone to imagine a future for our national cuisine that is as sustainable as it is delicious.
From the Trade Paperback edition.
Expanding on the film's themes, the book Food, Inc. will answer those questions through a series of challenging essays by leading experts and thinkers. This book will encourage those inspired by the film to learn more about the issues, and act to change the world.
The most up-to-date information about the more than 1,800 most commonly prescribed drugs in the United States:
• Generic and brand-name listings that can help you save money
• What the drug is for, and how it works
• Usual dosages, and what to do if a dose is skipped
• Side effects and possible adverse reactions, highlighted for quick reference
• Interactions with other drugs and food
• Overdose and addiction potential
• Alcohol-free and sugar-free medications
• The most popular self-injected medications and their safe handling
• Information for seniors, pregnant and breast-feeding women, children, and others with special needs
• Cautions and warnings, and when to call your doctor
• 32 pages of actual-size color photographs of prescription pills
From the Trade Paperback edition.
This book of clinical pharmacology covers the science of drugs or pharmaceutical including their origin, composition, pharmacokinetics, mechanism of action, therapeutic use, side effects and toxicology with specific description of drugs followed by short headings makes it easy to understand and point-wise explanation of information. This clinical pharmacology book will be helpful for the medical students and practicing doctors.
Visit us: www.kaniz.in
Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Sourcepresents an introduction to the chemical and biological properties of alkaloids isolated from M. speciosa as well as their synthetic analogs. The book covers various topics including phytochemistry, medicinal chemistry, and pharmacology. Current research, analgesic effects, and addiction potential are also discussed. As the first extensive text on the basic science and clinical use of Kratom, the book provides readers with a concise yet comprehensive introduction to nature’s "other opioid."
Like most Americans, Steve Ettlinger eats processed foods. And, like most consumers, he didn't have a clue as to what most of the ingredients on the labels mean. So when his young daughter asked, Daddy, what's polysorbate 60?, he was at a loss and determined to find out.
From the phosphate mines in Idaho to the oil fields in China to the Hostess factories and their practices, Twinkie, Deconstructed demystifies some of the most common processed food ingredients, where they come from, how they are made, how they are used, and why. Beginning at the source (hint: they're often more closely linked to rock and petroleum than any of the four food groups), we follow each Twinkie ingredient through the process of being crushed, baked, fermented, refined, and/or reacted into a totally unrecognizable goo or powder, all for the sake of creating a simple snack cake.
An insightful exploration of the modern food industry, if you've ever wondered what you're eating when you consume foods containing mono- and diglycerides or calcium sulfate (the latter a food-grade equivalent of plaster of paris), this book is for you. Consequently, as Hostess plans to permanently close its doors in 2012, this book will provide a relevant guide into the practices of one of the biggest companies of all time.
While Katz expertly contextualizes fermentation in terms of biological and cultural evolution, health and nutrition, and even economics, this is primarily a compendium of practical information—how the processes work; parameters for safety; techniques for effective preservation; troubleshooting; and more.
With two-color illustrations and extended resources, this book provides essential wisdom for cooks, homesteaders, farmers, gleaners, foragers, and food lovers of any kind who want to develop a deeper understanding and appreciation for arguably the oldest form of food preservation, and part of the roots of culture itself.
Readers will find detailed information on fermenting vegetables; sugars into alcohol (meads, wines, and ciders); sour tonic beverages; milk; grains and starchy tubers; beers (and other grain-based alcoholic beverages); beans; seeds; nuts; fish; meat; and eggs, as well as growing mold cultures, using fermentation in agriculture, art, and energy production, and considerations for commercial enterprises. Sandor Katz has introduced what will undoubtedly remain a classic in food literature, and is the first—and only—of its kind.
Author Sebastian Enfield had it all. A loving family, an up-and-coming career at a Fortune 500 company, good friends and an active social life. He was living the proverbial American dream. Until, that is, his life was sidetracked when he became addicted to painkillers. It all started with far-too-easy online purchases of narcotic pills, and eventually Sebastian “graduated” to heroin. As with most addicts, as his opiate habit developed his life began to unravel. Family, friends and career became less and less important. Maintaining his expensive addiction became the most important priority each day. But when a winter blizzard came one December and “his guy” stopped returning his phone calls, Sebastian knew another kind of storm was heading his way. Withdrawal. He suffered in bed for a few days before his dealer finally returned his calls and delivered the goods. But this was the final turning point. After all he had gone through, Sebastian knew things couldn’t continue like this. So he made arrangements to visit a Suboxone-prescribing doctor, and very shortly thereafter, he was finally on the long road to recovery.
But while being treated with Suboxone, Sebastian had some anxieties and a lot of questions. “How long should I really be on this stuff? Should I try to taper off or not? And if so, how do you do it so as to minimize any discomfort? What other things should I be doing to aid in my recovery?” He looked to the Internet for answers, but what he found was a lot of contradictory information, posts from people claiming that “this stuff is even worse than what I was on before!”, and even disagreement among doctors and other health professionals with regard to Suboxone treatment protocols. Sebastian suspected that if he found all this confusing, there were probably many others in the same boat.
And so, he set out to investigate all of this, and to write a book that explained his findings in clear and simple terms. Sebastian spoke with various doctors, Suboxone patients and therapists, and synthesized their views and opinions, along with his own experiences, into a book of tips and suggestions that would help doctors and patients best approach buprenorphine treatment.
Sebastian begins with his own compelling story, where he details the life journey that ultimately led to drug addiction. He then presents several suggestions and tips that cover a wide range of questions he knew Suboxone patients had. The book covers a variety of topics, such as how to best select a doctor, how to approach counseling (and whether you really need counseling), how to taper off the medication with minimal discomfort (and whether you even should taper off the medication), resources that may help with paying for treatment, and a variety of “lifestyle hacks” Sebastian found to be useful while being treated. Sebastian lays all of this out clearly, and provides a positive and motivating read that will help patients understand that treatment with buprenorphine need not be a scary and uncertain thing. On the contrary, it can be a constructive part of recovery from opiate addiction. As he put it, “This is the book I wish I had when I began buprenorphine treatment.”
The highly-anticipated paperback edition of The Elements is finally available.
An eye-opening, original collection of gorgeous, never-before-seen photographic representations of the 118 elements in the periodic table.
The elements are what we, and everything around us, are made of. But how many elements has anyone actually seen in pure, uncombined form? The Elements provides this rare opportunity. Based on seven years of research and photography, the pictures in this book make up the most complete, and visually arresting, representation available to the naked eye of every atom in the universe. Organized in order of appearance on the periodic table, each element is represented by a spread that includes a stunning, full-page, full-color photograph that most closely represents it in its purest form. For example, at -183°C, oxygen turns from a colorless gas to a beautiful pale blue liquid.
Also included are fascinating facts, figures, and stories of the elements as well as data on the properties of each, including atomic weight, density, melting and boiling point, valence, electronegativity, and the year and location in which it was discovered. Several additional photographs show each element in slightly altered forms or as used in various practical ways. The element's position on the periodic table is pinpointed on a mini rendering of the table and an illustrated scale of the element's boiling and/or melting points appears on each page along with a density scale that runs along the bottom.
Packed with interesting information, this combination of solid science and stunning artistic photographs is the perfect gift book for every sentient creature in the universe.
Includes a tear-out poster of Theodore Gray's iconic Photographic Periodic Table!
Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.
Most DIY cheesemaking books are hard to follow, complicated, and confusing, and call for the use of packaged freeze-dried cultures, chemical additives, and expensive cheesemaking equipment. For though bread baking has its sourdough, brewing its lambic ales, and pickling its wild fermentation, standard Western cheesemaking practice today is decidedly unnatural. In The Art of Natural Cheesemaking, David Asher practices and preaches a traditional, but increasingly countercultural, way of making cheese—one that is natural and intuitive, grounded in ecological principles and biological science.
This book encourages home and small-scale commercial cheesemakers to take a different approach by showing them:
• How to source good milk, including raw milk;
• How to keep their own bacterial starter cultures and fungal ripening cultures;
• How make their own rennet—and how to make good cheese without it;
• How to avoid the use of plastic equipment and chemical additives; and
• How to use appropriate technologies.
Introductory chapters explore and explain the basic elements of cheese: milk, cultures, rennet, salt, tools, and the cheese cave. The fourteen chapters that follow each examine a particular class of cheese, from kefir and paneer to washed-rind and alpine styles, offering specific recipes and handling advice. The techniques presented are direct and thorough, fully illustrated with hand-drawn diagrams and triptych photos that show the transformation of cheeses in a comparative and dynamic fashion.
The Art of Natural Cheesemaking is the first cheesemaking book to take a political stance against Big Dairy and to criticize both standard industrial and artisanal cheesemaking practices. It promotes the use of ethical animal rennet and protests the use of laboratory-grown freeze-dried cultures. It also explores how GMO technology is creeping into our cheese and the steps we can take to stop it.
This book sounds a clarion call to cheesemakers to adopt more natural, sustainable practices. It may well change the way we look at cheese, and how we make it ourselves.
Presenting theoretical knowledge and applied practical considerations, this title
provides an in-depth discussion of recent advances in sterilization
identifies obstacles that may be encountered at any stage of the validation program, and suggests the newest and most advanced solutions
explores distinctive and specific process steps, and identifies critical process control points to reach acceptable results
blends the use of theoretical knowledge with recent technological advancements to achieve applied practical solutions
· The average American carries a "body burden" of 700 synthetic chemicals;
· Chemicals in tap water can cause reproductive abnormalities and hermaphroditic birth;
· One study of lactating women found perchlorate (a toxic component of rocket fuel) in practically every mother's breast milk.
In the face of this national health crisis, Fitzgerald presents informed and practical suggestions for what we can do to turn the tide and live healthier lives.
From the Trade Paperback edition.
Includes New and Updated Material
Now in its second edition, this work is the culmination of research and discussions with technical experts, as well as USP and FDA representatives on various topics of interest to the pharmaceutical microbiologist and those responsible for the microbial quality of products, materials, equipment, and manufacturing facilities. New in this edition is an entire chapter dedicated to the topic of biofilms and their impact on pharmaceutical and biopharmaceutical operations. The subject of rapid methods in microbiology has been expanded and includes a discussion on the validation of alternative microbiological methods and a case study on microbial identification in support of a product contamination investigation.
Substantially updated and revised, this book assists readers in understanding the fundamental issues associated with pharmaceutical microbiology and provides them with tools to create effective microbial contamination control and microbial testing programs for the areas under their responsibility.
Expanding on the film's themes, the book Food, Inc. will answer those questions through a series of challenging essays by leading experts and thinkers. This book will encourage those inspired by the film to learn more about the issues, and act to change the world.
With global population numbers projected to increase by 2 billion by 2050, a veritable food crisis is on the horizon. In this eBook, Can We Feed the World? The Future of Food, we examine some of the complex causative factors involved in the coming "food crisis" and the innovative ideas and technologies designed to increase food production sustainably. We also examine current industry methods to increase production and the controversies surrounding them, including not only hot-button issues like genetically modified (or GM) and processed foods, but also food safety and the physical effects of the modern diet. To start the discussion, Jonathan Foley throws down the gauntlet with the first article, "The Grand Challenge: Can We Feed the World and Sustain the Planet?" In it he takes a macroscopic look at the coming crisis and presents five solutions that could both double the world's food production by mid-century as well as decrease greenhouse gas emissions and curb environmental damage. Other articles discuss technologies ranging from more sustainable offshore fish farming to "vertical farms," and an entire section tackles GM crops. Hugely controversial, GM crops are either the magic bullet that will save millions from starvation or Frankenstein's monster. To that end, don't miss Sasha Nemecek's "The Pros and Cons of GM Foods," in which she interviews experts on both sides of this issue, as well as "Three Myths about Genetically Modified Crops," by Natasha Gilbert. Later, we delve into the processed food industry, taking a magnifying glass to fast food and high fructose corn syrup, as well as food safety issues, including monitoring sources of contamination as well as preventing food poisoning. With all the possibilities on the horizon—from GM crops to new technologies in farming and fishing—world hunger does not have to be inevitable, but we'll need to be resourceful in managing the food supply so that we can preserve the planet and ourselves.
New chapters on:
-Supplemental processes including filtration, sedimentation, centrifugation, and mixing
-Extrusion processes for foods
-Packaging concepts and shelf life of foods
Expanded information on
Emerging technologies, such as high pressure and pulsed electric field
Transport of granular foods and powders
Process controls and measurements
Design of plate heat exchangers
Impact of fouling in heat transfer processes
Use of dimensional analysis in understanding physical phenomena
Indeed, this book fills a big hole in the market. Beginner guides leave you wanting more content and explanation of process, while recipe-based cookbooks often fail to dig deeper into the science, and therefore don’t allow for a truly intuitive cheesemaker to develop. Acclaimed cheesemaker Gianaclis Caldwell has written the book she wishes existed when she was starting out. Every serious home-scale artisan cheesemaker—even those just beginning to experiment—will want this book as their bible to take them from their first quick mozzarella to a French mimolette, and ultimately to designing their own unique cheeses.
This comprehensive and user-friendly guide thoroughly explains the art and science that allow milk to be transformed into epicurean masterpieces. Caldwell offers a deep look at the history, science, culture, and art of making artisan cheese on a small scale, and includes detailed information on equipment and setting up a home-scale operation. A large part of the book includes extensive process-based recipes dictating not only the hard numbers, but also the concepts behind each style of cheese and everything you want to know about affinage (aging) and using oils, brushes, waxes, infusions, and other creative aging and flavoring techniques. Also included are beautiful photographs, profiles of other cheesemakers, and in-depth appendices for quick reference in the preparation and aging room. Mastering Artisan Cheesemaking will also prove an invaluable resource for those with, or thinking of starting, a small-scale creamery.
Let Gianaclis Caldwell be your mentor, guide, and cheering section as you follow the pathway to a mastery of cheesemaking. For the avid home hobbyist to the serious commercial artisan, Mastering Artisan Cheesemaking is an irreplaceable resource.
Developed for use at the point of care, Pharmacotherapy Bedside Guide helps you decide which pharmacotherapy to employ in specific clinical situations. Comprised exclusively of quick-hit tables and algorithms, this carryanywhere companion tells you what treatment the evidence suggests for each illness or disorder. It also details essential drug information, such as benefits, risks, adverse reactions, dosage, interactions with other drugs, and responses. Conveniently organized by specialty and disorder rather than drug, Pharmacotherapy Bedside Guide will prove invaluable when treating patients.
All these problems have been shielded from public scrutiny because they're too complex to capture in a sound bite. But Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct in the medical industry affects us on a global scale.
With Goldacre's characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for regulation. This is the pharmaceutical industry as it has never been seen before.
Drawing from personal experience as well as scientific literature, this book introduces the core concepts of winemaking before delving into methods and analysis to provide practical insights into creating and maintaining quality in the wine product.Understand the chemistry and sensory science at the foundation of quality winesExplore real-world examples of key analysis and application of conceptsPractice methods and exercises for hands-on experience
Here, Dr. Mann, a nationally recognized hypertension specialist, identifies the drugs most likely to have side effects, and those that can be used in their place. He describes the shortcomings of some of the new drugs, while also introducing readers to some excellent old drugs that are woefully underused as a result of the publicity blitz surrounding the new, expensive ones. He emphasizes the importance of matching the medication and dosage to the individual who will be taking them, and presents the overlooked clues that can tell us who should be on which drug (even an excellent drug can be the wrong one if it is given to the wrong person or in the wrong dose). Hypertension and You is directed at the more than 50 million Americans (including a majority of people over the age of 60) who are taking blood pressure medication. Many patients suspect they might be on the wrong medication, but don’t know enough to be sure. This book shows how medications can be prescribed more wisely to achieve better results and gives patients the knowledge they need to capably discuss their medications with their health care providers.
Hypertension and You provides many ideas and approaches that will be new to readers, and also to many physicians, and which no other book offers. It’s the first book to make the case that something is terribly wrong with how doctors are prescribing drugs for this condition. It provides readers with better knowledge of the available medications, empowering them to work with their physician to get onto the medications that are right for them.
The Essentials For Dummies Series
Dummies is proud to present our new series, The Essentials For Dummies. Now students who are prepping for exams, preparing to study new material, or who just need a refresher can have a concise, easy-to-understand review guide that covers an entire course by concentrating solely on the most important concepts. From algebra and chemistry to grammar and Spanish, our expert authors focus on the skills students most need to succeed in a subject.
"These cards offer concise yet detailed case studies for students to review current pharmacotherapeutic options for many of the commonly encountered disease states....Students might find these cards to be a very helpful in addition to their therapeutics courses to help them retain knowledge through the use of real-life clinical scenarios. 3 Stars."--Doody's Review Service
These 238 Q&A cards provide a complete review of pharmacotherapeutic concepts for the major disease states most often encountered in practiceEmphasizes evidence-based therapeutic decision making and drug therapy monitoring Each card features a case and therapeutic question Key facts are included for the drug or drug class that correctly answers the question Case Notes explain the answer and include clinical pearls about use of the drug, management of the disease, and dosing
Miracle Medicines goes behind the scenes of the pharmaceutical industry and into the high-security laboratories to tell the stories of the men and women---chemists, physiologists, medical and clinical researchers, engineers---who have chosen to toil for years in the lab in order to transform scientific theories into new lifesaving medicines.
You’ll witness the day-to-day labors, victories and defeats of the dedicated professionals who are waging a war against the diseases that still plague mankind. From the confines of their laboratories, these pharmaceutical adventurers explore unknown territories in health and science.
Miracle Medicines reveals what really happens during the long and uncertain journey that each new drug and its creators must endure from theory, to research, to testing and, finally, FDA approval and delivery to the public. It’s a very human story within the context of fascinating scientific innovation.
Through first hand interviews you’ll also meet the patients who benefit from these manmade miracles and learn how, within their bloodstreams, an ongoing battle is raging. The drugs profiled are:Advair: GlaxoSmithKline’s revolutionary asthma medication, the first packaged as both a control and emergency drug.Gleevec: The Novartis’ chronic myeloid leukemia treatment born from decades of medical research in a field of study that was once considered hopeless.Humalog: Eli Lilly’s reinvention of insulin to control diabetes has been described as being better than natureLipitor: Pfizer’s miracle antidote for high cholesterol that was nearly lost to the pharmaceutical vaults and has since become the world’s top-selling medicine.Norvir: Abbott’s contribution to the fight against HIV that nearly erases all traces of the disease from the bloodstream and prolongs the life of patients.Remicade: Created for the treatment of Crohn’s disease, rheumatoid arthritis and other Immune Mediated Inflammatory Diseases, Johnson & Johnson’s revolutionary biomedicine was developed from technology that once was only found in science fiction.Seroquel: AstraZeneca’s treatment for both schizophrenia and bipolar mania that has given millions of psychiatrics a new lease on life.
This compelling and truth-revealing book will forever change the way you view the medicines in your medicine cabinet, and the people who create them.
The authors offer a basic introduction to pharmacological concepts, embedded in specific conditions, through case studies and self-assessment questions. By utilising a case study approach, they enable the reader to link pharmacological concepts with clinical practice.
Many of the conditions presented will be seen across all healthcare settings. In addition, the comprehensive glossary and list of abbreviations will enable students to understand some of the more technical terms used in the British National Formulary (BNF) and other prescribing sources.
Reading this book, and carrying out the numerous self-assessment activities, will give the reader an appreciation of the value of having a sound pharmacological knowledge base in order to deliver safe practice, effective prescribing and improved patient care.
How the body affects drugs
How drugs affect the body
Types of adverse drug reactions and interactions
Understanding and using the British National Formulary
Chronic obstructive pulmonary disease
Incontinence in adults
Mental health problems
Complex health needs and polypharmacy
The challenges of non-medical prescribing
Speed-Speed-Speedfreak traces the criminal and cultural use of amphetamine and its growing use through each new and destructive cycle. The book will be printed in rounded pill capsule form, like the vaunted “black beauty” of pharmaceutical history.
Mick Farren is the former lead singer of The Deviants and the author of more than forty books.
* Only available work to cover the entire whisky process from raw material to delivery to the market in such a comprehensive manner
* Includes a chapter on marketing and selling whisky
* Foreword written by Alan Rutherford, former Chairman and Managing Director of United Malt and Grain Distillers Ltd.
Now in its 5th Edition, the highly acclaimed Principles of Food Sanitation provides sanitation information needed to ensure hygienic practices and safe food for food industry personnel as well as students. The highly acclaimed textbook and reference addresses the principles related to contamination, cleaning compounds, sanitizers, cleaning equipment. It also presents specific directions for applying these concepts to attain hygienic conditions in food processing or food preparation operations.
New features in this edition include:
A new chapter on the concerns about biosecurity and food sanitation
Updated chapters on the fundamentals of food sanitation, contamination sources and hygiene, Hazard Analysis Critical Control Points, cleaning and sanitizing equipment, and waste handling disposal
Comprehensive and concise discussion about sanitation of low-, intermediate-, and high-moisture foods
Let's get drunk!
Grab your copy now!
Water Insolubility is the Primary Culprit in over 40% of New Drug Development Failures
The most comprehensive resource on the topic, this second edition of Water Insoluble Drug Formulation brings together a distinguished team of experts to provide the scientific background and step-by-step guidance needed to deal with solubility issues in drug development. Twenty-three chapters systematically describe solubility properties and their impact on formulation, from theory to industrial practice. With detailed discussion on how these properties contribute to solubilization and dissolution, the text also features six brand new chapters on water-insoluble drugs, exploring regulatory aspects, pharmacokinetic behavior, early phase formulation strategies, lipid based systems for oral delivery, modified release of insoluble drugs, and scalable manufacturing aspects. The book includes more than 15 water-insoluble drug delivery systems or technologies, illustrated with case studies featuring oral and parenteral applications. Highlighting the most current information and data available, this seminal volume reflects the significant progress that has been made in nearly all aspects of this field.
Side Effects tells the tale of a gutsy assistant attorney general who, along with an unlikely whistle-blower at an Ivy League university, uncovered evidence of deception behind one of the most successful drug campaigns in history. Paxil was the world's bestselling antidepressant in 2002. Pediatric prescriptions soared, even though there was no proof that the drug performed any better than sugar pills in treating children and adolescents, and the real risks the drugs posed were withheld from the public. The New York State Attorney General's office brought an unprecedented lawsuit against giant manufacturer GlaxoSmithKline, the maker of Paxil, for consumer fraud. The successful suit launched a tidal wave of protest that changed the way drugs are tested, sold, and marketed in this country.
With meticulous research, Alison Bass shows us the underbelly of the pharmaceutical industry. She lays bare the unhealthy ties between the medical establishment, big pharma, and the FDA—relationships that place vulnerable children and adults at risk every day.
A Doody's Core Title for 2017!
Pharmacotherapy Handbook provides the critical information you need to make drug therapy decisions for more than 140 diseases and disorders commonly encountered in a clinical setting. Featuring a convenient alphabetized presentation, this handy guide utilizes text, tables, figures, and treatment algorithms to make important drug data readily accessible and easily understood.
Features:Consistent chapter organization includes: Disease state definition Concise review of relevant pathophysiology Clinical presentation Diagnosis Goals of treatment Treatment Monitoring Six appendices, including "Allergic and Pseudoallergic Drug Reactions" and "Geriatrics" The ideal companion to Pharmacotherapy: A Pathophysiologic Approach, Ninth Edition by Joseph DiPiro, et al