A supernatural thriller starring Nicolas Cage as down-on-his-luck truck driver Joe who is haunted by the memory of his deceased wife and child. When Joe meets Julie (Franka Potente, Taboo), a spiritually gifted woman who enlists him in a desperate effort to find the lost soul of her comatose daughter, Billie (Penelope Mitchell, Hellboy). But the spirit of Joe's dead wife Mary proves stronger, possessing the young woman's body and determined to settle her unfinished business with the living.