An intense thriller set against the backdrop of the opioid epidemic, Crisis features three interwoven stories that highlight the greed, violence and tragedy of the drug war. A drug trafficker arranges a multi-cartel Fentanyl smuggling operation, an architect recovering from an oxycodone addiction tracks down the truth behind her son's disappearance and a university professor battles unexpected revelations about his employer, a pharmaceutical giant bringing a new "non-addictive" painkiller to market.