Two-time Academy Award nominee® Ethan Hawke plays Edward Dalton, a researcher in the year 2019, in which an unknown plague has transformed the world's population into blood-thirsty vampires. As the human population nears extinction, vampires must capture and farm every remaining human, or find a blood substitute before time runs out. However, a covert group of vampires makes a remarkable discovery, one which has the power to save the human race.