The movie revolves around Easwaran alias E (Jiiva), an orphan brought up in the musty, teeming slums of Chennai by an old woman. For him money is the thing in life, he does anything for that. He Comes across Jothy (Nayantara), a bar dancer, who settles down in the same locality. After a few encounters they get acquainted with each other. E's simple ways attract Jothy. Coming to know of his past, Jothy tries desperate to correct his ways and set him on the right path. Meanwhile Dr Ramakrishnan (Ashish Vidyarthi) takes up the task of testing a medicine devised by a foreign company, which may come handy in ing people in thousands especially during times of wars. Dr Ramakrishnan chooses Jothy's sister and E's grandmother as specimen for the test. He cashes in on the ignorance to slum-dwellers. Things take a turn, when E rescues Dr Ramakrishnan from a bid by Nellai Mani (Pasupathy).Watch the full movie to know the rest of the story.