When Jessie (Rebecca Romijn-Stamos) and Paul’s (Greg Kinnear) eight year old son Adam is tragically killed on his birthday, Richard (Robert De Niro), a doctor on the forefront of genetic research, befriends his former student Jessie and her husband at the height of their mourning. He leads the couple in a desperate attempt to reverse the rules of nature and clone their son. The experiment is successful and under Richard’s watchful eye, Adam grows into a healthy and happy young boy, until his 8th birthday, when the new Adam begins to suffer from night terrors and horrific flashbacks and a sinister new personality begins to emerge.