The Man from U.N.C.L.E. travels to Europe to thwart a fiendish plot by THRUSH to control a machine that can make humans younger in One of Our Spies is Missing. Master spy Illya Kuryakin (David McCallum--"The Man from U.N.C.L.E.") is on the trail of a mysterious string of disappearing cats when his path crosses with his partner, Napoleon Solo's (Robert Vaughn--"The Man from U.N.C.L.E."), investigation of a missing scientist. Together, they follow the twisting trail of the scientist who has been using cats to experiment on his rejuvenation machine--a device sought by both the evil minds behind THRUSH and a deadly syndicate of high fashion models.