Kristen Wiig and Bill Hader play a pair of estranged siblings who are reconnected at a particularly dark moment for both in the Sundance drama The Skeleton Twins. And, when a depressed Milo (Hader) leaves Los Angeles to live with a similarly depressed Maggie (Wiig) and her earnest, goofy husband (Luke Wilson), itโs not exactly a seamless homecoming, with fights, lies, and past traumas weighing on the once-inseparable twins throughout.