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Everything had been going according to plan for fast-talking New Yorker Zoe Hart (series star RACHEL BILSON). Beautiful, privileged and talented, she was on her way to becoming a heart surgeon, just like her father. But when she's told she doesn't have the requisite bedside manner to get an important fellowship she was counting on getting тАФ that she doesn't have the heart to be a heart surgeon тАФ Zoe's devastated. Desperate, she decides to finally accept the offer of a kindly stranger, Dr. Harley Wilkes (guest star NICHOLAS PRYOR -- Beverly Hills, 90210), whom she met at her medical school graduation, and who had proposed she join his small medical practice in Bluebell, Alabama. When Zoe arrives in quaint, picturesque Bluebell, she is instantly befriended by a handsome lawyer тАФ and the town's golden boy тАФ George Tucker (series star SCOTT PORTER). George is excited to discover that Zoe is from New York, where he lived for several years before returning to his hometown.