After being shot in the line of duty, New York Detective Robert Ironside (Blair Underwood) swore he would never let a wheelchair slow him down. Undeterred, he drives his elite, hand-picked team, including Virgil (Pablo Schreiber), Holly (Spencer Grammer) and Teddy (Neal Bledsoe), to solve the city's most difficult and notorious crimes. Watching over them is their boss, Capt. Ed Rollins (Kenneth Choi), who shares a mutual respect with Ironside, while Gary (Brent Sexton) is Robert's scrappy ex-partner who marvels at his determination and ability to piece together his life after being shot.