Hotshot New York publicist-to-the-stars Jake Phillips (John Stamos) is tired of all the serial womanizing he does (must be rough) and decides it's time for him to find the woman of his dreams, his soulmate, despite the protests of his married best friend, Adrian, that the grass isn't always greener in a relationship. Jake's boss at Magnum PR, Naomi, provides unsentimental clarity when Jake needs it, and needy performance artist Patrick is always there for Jake -- whether he likes it or not and whether the time is appropriate or not.