Marvel Comics Spider-Man

Still dealing with the loss of Mary Jane, Spider-Man's friend Robbie is framed of a crime. Spider-Man works with J. Jonah Jameson to clear his name.

Doctor Octopus attempts to blackmail the Hardy family with his knowledge of their ties to the legendary burglar known as The Cat, but is coerced into helping the Kingpin, who also has plans for The Cat, namely kidnapping him from his cell in S.H.I.E.L.D headquarters and forcing him to reveal his knowledge of the Super Soldier formula that created Captain America. Spider-Man tries but fails to stop the kidnapping during his own investigation into the Hardys and The Cat.

With the serum in hand, Kingpin successfully tests it on Felicia Hardy, The Cat's daughter. Now the superpowered Black Cat, Felicia teams up with Spider-Man to rescue her father and stop Kingpin from using the serum for his own ends.

After Dr. Crawford is mutated into a monster, Spider-Man and Black Cat team up with Kraven to help her. Dr. Curt Conners finds an antidote and cures her.

Alistair Smythe kidnaps the Black Cat after she has been knocked out by strange green gas, leaving Spider-man helpless to save her, Spider-Man is hired to capture either Scorpion or the Vulture to free the Black Cat. The Scorpion and Spider-man are used in effort to transform Silvermane back into an adult. But the Vulture arrives and drains the youth from Silvermane turning him into an old man once again. Spider-Man finally agrees to become Black Cat's partner.

Debra Whitman finds Michael Morbius, and announces her plan to use Doc Connors' Neogenic Recombinator to revive him. Shocker and Landon arrive, and kidnap Morbius. Black Cat, Spider-Man and Whistler rescue Morbius and return him to the living vampire state that he was before.

Blade returns to stop his mother, the Vampire Queen. She tries convince Morbius to reveal his knowledge of the Neogenic Recombinator. When he does, she uses it to create more vampires. She is eventually stopped by Spider-Man, Black Cat, Morbius, and Blade. The Black Cat decides to then leave Spider-man to fight alongside Morbius and Blade.

Harry Osborn follows his father's footsteps and becomes the new Green Goblin in an effort to kill Spider-Man. Meanwhile, the Punisher seeks to find out if Peter Parker knows where Mary Jane Watson is. In the end, "Mary Jane" is back, but she can't remember what happened to her at the last fight with the first Green Goblin.

Spider-Man teams up with Mysterio, who has built a robotic Rhino, Doc Ock, Lizard, Venom and Carnage, to rescue "Mary Jane" who was kidnapped by Mysterio's girlfriend. After rescuing her, Spider-Man tells "Mary Jane" the truth about his identity.

Doc Connors and "Mary Jane" are kidnapped by lizard people from the sewers, who claim that Connors created them. Spider-Man buys "Mary Jane" time so she can escape and find Margaret Conners, who has a device that can cure all the creatures.

Hobie Brown is enlisted as the Prowler by the Kingpin. Hobie's forced to wear a special suit with a belt that will detonate if he tampers with it. Spider-Man and Prowler team up against the Kingpin, so Hobie can have a chance at returning to a normal life.