The doctors and nurses of Chicago Med brace for an influx of trauma patients when a pre-dawn pileup finds the hospital in full scramble mode. With Dr. Rhodes (Colin Donnell) and Dr. Latham (guest star Ato Essandoh) handling duties in triage, difficult decisions are made. As a result of the storm and emergencies, supplies become limited and Goodwin (S. Epatha Merkerson), Dr. Manning (Torrey DeVitto) and Dr. Halstead (Nick Gehlfuss) must deal with making an impossible decision. Meanwhile, Dr. Choi (Brian Tee) handles a severely burned patient who has one final request. Dr. Charles (Oliver Platt) deals with an agitated patient who makes his presence known in the waiting room. Marlyne Barrett, Yaya DaCosta and Rachel DiPillo also star. Jesse Spencer, Taylor Kinney, Eamonn Walker, Kara Killmer, David Eigenberg, Jeff Hephner and Eddie Jemison also guest star.