Supernatural

In the fourth season premiere, it's been four months since Dean was dragged away by the hounds of Hell, the result of a deal he made with the Crossroads Demon in exchange for his brother's life. Now, Dean wakes up in a pine box. He's been freed from Hell, but he doesn't know how or why. He has a joyful reunion with Sam and fellow demon hunter Bobby (recurring guest star JIM BEAVER), but it isn't long before the three start to really wonder what exactly pulled Dean from Hell -- and what it will want in return.

Sam and Dean are stunned when the spirits of Meg (recurring guest star NIKKI AYCOX - "Cold Case," "Ed") and Agent Henricksen (recurring guest star C. MALIK WHITFIELD - "The Guardian") appear and accuse the Winchesters of failing them. Although rattled, the brothers must pull together to save Bobby (recurring guest star JIM BEAVER), who is too crippled with guilt to fight off the angry ghosts of the young children he couldn't save.

Dean is transported back in time and is shocked when he lands in Lawrence, Kansas. However, that shock turns to amazement after he runs into a young John Winchester (guest star MATTHEW COHEN - "South of Nowhere," "Medium") and Mary (guest star AMY GUMENICK - "Greek") who have just fallen in love. Dean isn't sure why he was sent back so he begins to enjoy the time with his parents and newfound grandfather (guest star MITCH PILEGGI - "The X-Files," "Stargate: Atlantis"), who may be hiding a secret that is key to Sam and Dean's entire predicament.

Sam and Dean find that a family man (guest star DAMEON CLARK - "24," "Prison Break," "Dragon Ball Z" series), is turning into a flesh-eating monster, and argue about killing him.

Shown entirely in black and white, Dean and Sam investigate several murders at Oktoberfest. The first victim was found with bite marks on her neck, much like a vampire would leave, while the second victim has wounds that look like a werewolf attack. After a mummy rises from his crypt, Dean determines that a shape-shifter demon is terrorizing the town as iconic monsters from the old Hollywood movies.

Dean is infected with an illness that starts as anxiety, but moves to full-blown terror that stops the heart. Sam and Bobby (JIM BEAVER) must find the root before Dean dies.

The brothers deduce a witch is sacrificing people to summon a dangerous demon. ROBERT WISDOM ("The Wire," "Prison Break") guest stars as Uriel, a specialist angel.

Sam and Dean investigate a small town where a wishing well works so well that a teddy bear comes to life, someone wins the lottery and the town geek gets a hot girlfriend. The brothers realize, however, that while everyone is happy now, the end result could be disastrous.

Ruby (GENEVIEVE CORTESE - "Wildfire"), Sam and Dean look for a girl (JULIE McNIVEN - "Mad Men") who hears the angels. Castiel (MISHA COLLINS) and Uriel (ROBERT WISDOM) return.

Anna (JULIE McNIVEN) recalls her past and Sam and Dean understand why Castiel (MISHA COLLINS) and Uriel (ROBERT WISDOM) want her dead. Alastair (MARK ROLSTON) gets closer.

Sam and Dean investigate the appearance of a young female ghost in an abandoned house, but things become more complicated when a family moves in.

BARRY BOSTWICK, JOHN RUBENSTEIN and RICHARD LIBERTINI guest star as three friends who used to be famous magicians but have since been replaced by younger and flashier tricks.

Sam and Dean go undercover at their old high school, causing them to flash back to the time they spent there, when Sam was picked on by the school bully and Dean was Mr. Popular.

Sam and Dean find three small town men have beaten their wives to death. Behind the murders is a siren, who puts the brothers under her spell and pits them against each other.

Pamela (TRACI DINWIDDIE) sends the boys to the spiritual world when they find people cheating death. They must face Alastair (CHRISTOPHER HEYERDAHL), who is kidnapping the Reapers.

Castiel (MISHA COLLINS) and Uriel (ROBERT WISDOM) capture Alastair (CHRISTOPHER HEYERDAHL), and ask Dean to torture him with skills he learned in Hell.

What would happen if the Winchesters weren't hunters? In this alternate life, Dean is a corporate man who enjoys health drinks and listens to news radio and Sam is in tech support

Sam and Dean discover "Supernatural," a series of comic books that accurately detail their lives as demon hunters. Lilith (KATHERINE BOECHER) is coming and she has plans for Sam.

A 19-year-old boy named Adam (guest star JAKE ABEL - "Flash of Genius") calls Sam and Dean looking for John Winchester; the boy claims to be his son. Dean and Sam meet Adam, assuming he's a demon trying to lure them into a trap. However, they find out that John was, indeed, the boy's father and Dean is infuriated when he hears Adam tell of his "normal" upbringing.

Castiel (recurring guest star MISHA COLLINS) appears to Dean in a dream and says he has something important to tell him but they need to meet somewhere private. Dean and Sam go searching for Castiel, but instead find Castiel's human vessel, who has only a spotty recollection of being an angel and wants to return to his family and normal life. Dean and Sam, however, are concerned about his safety.

Dean and Bobby (recurring guest star JIM BEAVER) lock Sam in Bobby's panic room so he can detox from the demon blood. However, as Bobby sees more seals are being broken he tells Dean they should let Sam out to help them fight the impending apocalypse. Dean disagrees and goes to Castiel (recurring guest star MISHA COLLINS) for help. Sam and Dean have a big blowout confrontation.

The apocalypse is coming, and Sam and Dean prepare for the fight in very different ways. Sam joins Ruby (recurring guest star GENEVIEVE CORTESE) on a final run to kill Lilith (recurring guest star KATHERINE BOECHER), while Castiel (recurring guest star MISHA COLLINS) and Zachariah (guest star KURT FULLER) tell Dean it's time to play his part in stopping Lucifer.