4 new endings (2 in the storyline of Jack and 2 in the line of John), now the total number of endings is 9.
Additional quest "Delirium Door", the passage of which contains one of the new endings.
Drawings of patients, like notes collected in a separate collection as the game progresses.
Maps of floors and other places of the hospital.
Graffiti containing a large amount of information.
New creepy creatures and more likely to die.