The Neuropathy Tracker is a Mobile Health (mHealth) tool for ambulatory self-assessment of neuropathy, which can be done by the patient at home. The app was designed in an iterative, user-centered design (UCD) process involving neurologists, patients, and healthy subjects, thereby ensuring a high degree of clinical validity and usability. The assessment methodology in the app applies state-of-the-art neuropathy assessment methods, and the app embodies a user-friendly and systematic assessment flow that guides the patient through the self-assessment. The Neuropathy Tracker tool was subject to a small feasibility study (N=17), which showed a statistically significant (Pearson correlation ρ= 0.86, p<0.05) but moderate (Concordance Correlation Coefficient (ρc) = 0.69) concurrent validity when compared with a standard clinical assessment method. All patients were able to complete the self-assessment without any help.