Alex de Campi is well known for her 2005 mini-series Smoke (published by IDW Publishing, art by Igor Kordey), which was nominated for the Eisner Award for Best Limited Series, and her 2006 manga series Kat & Mouse (published by Tokyopop, art by Federica Manfredi). De Campi's work falls outside the superhero genre, with Smoke being a political thriller, and Kat & Mouse detailing the adventures of two mystery-solving high school students (a "CSI for tweens"); she has published work for children (e.g. Agent Boo) and for the European market (e.g. her French language sci-noir series Messiah Complex).
Her other work includes the Valentine mobile comic, which is the main focus of her column Uncanny Valleygirl at the comics industry website Bleeding Cool. The author lives in London, England.