The major alterations addressed in the 7th Edition concern carcinomas of the oesophagus and the gastroesophageal junction, stomach, lung, appendix, biliary tract, skin, and prostate. In addition, there are several entirely new classifications:
A new approach has also been adopted to separate anatomical stage groupings from prognostic groupings in which other prognostic factors are added to T, N, and M categories. These new prognostic groupings, as well as the traditional anatomical groupings, are presented for oesophageal and prostate carcinomas.
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Leslie H. Sobin, MD, is in the Division of Gastrointestinal Pathology at the US Armed Forces Institute of Pathology (AFIP) in Washington, DC, USA.
Christian Wittekind, MD, is Professor of Medicine at the Institute for Pathology at the University of Leipzig, Germany.
Both Dr. Sobin and Dr. Wittekind represent a large international panel of oncology and oncologic pathology experts who contribute regularly to each new edition of the TNM Classification.