Organic Synthesis with Enzymes in Non-Aqueous Media

Giacomo Carrea · Sergio Riva

Apr. 2008 · Verkauft von John Wiley & Sons

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Closing a gap in the literature, this comprehensive book examines and discusses different non-aqueous systems from organic solvents to ionic liquids for synthetic applications, thus opening the door to new successful methods for biocatalytic reactions. It gathers into one handy source the information otherwise widely spread throughout the literature, combining useful background information with a number of synthetic examples, including industrial scale processes for pharmaceutical and fine chemicals.
Extremely well structured, the text introduces the fundamentals of non-aqueous enzymology, before going on to new reaction media and synthetic applications using hydrolases and non-hydrolytic enzymes.
The one-stop reference for everyone working in this hot field.

Autoren-Profil

Dr. Giacomo Carrea joined the Italian National Research Council (CNR) in 1969 where presently he is Director of the Institute of Chemistry of Molecular Recognition. He has been working in such fields as enzyme catalysis in organic solvents, synthesis of fine chemicals catalyzed by hydrolases, dehydrogenases, peroxidases and monooxygenases, study of conformation of proteins and polypeptides and analytical applications of bioluminescent enzymes. He is a member of the Editorial Board of "Trends in Biotechnology" and "Biocatalysis and Biotransformation" and the author of about 220 publications in international peer reviewed journals.

Dr. Sergio Riva is a Senior Research Scientist at the Institute of the Chemistry of Molecular Recognition. He took his Laurea in Chemistry in 1983 and his Diploma di Specialita? in Organic Synthesis in 1989. In 1987 he was at M.I.T. (USA) working with Prof. A. Klibanov. In 1993 he was awarded the Ciamician medal by the Organic Chemical Division of the Italian Chemical Society for his research activity in biocatalysis, presently documented by more than 150 publications reporting on the isolation and characterization of enzymes and on the synthetic exploitation of these biocatalysts.