Plant Design and Manufacturing Principles in DNA Vaccine Production
sep. 2020 · GRIN Verlag
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Bachelor Thesis from the year 2017 in the subject Chemistry - Bio-chemistry, grade: 80.0, University of Birmingham (Engineering), course: Chemical Engineering, language: English, abstract: This paper covers a detail design and cost (to an accuracy of +/- 20 percent) for a new manufacturing facility to produce DNA vaccines to be built on a greenfield site. Applied current good manufacturing practice (cGMP) and complied with all the regulatory guidelines set up by various agencies. The demand for DNA vaccines in large quantities at high purity for gene therapy is on the increase. As it helps to stimulate antibodies production in human and provide immune protection against many diseases such as cancer, malaria, HIV and other diseases and have potential advantages over conventional vaccines.
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