Gene Regulation, Epigenetics and Hormone Signaling

· Sold by John Wiley & Sons
Ebook
668
Pages

About this ebook

Das erste Referenzwerk dieser Art mit einer umfassenden und dennoch prägnanten Einführung in die Epigenetik beschäftigt sich mit den unzähligen Interaktionen zwischen Hormonregulation und Epigenetik. Die Inhalte sind gut strukturiert. Es gibt keine Überschneidungen zwischen den Kapiteln und jedes Kapitel beinhaltet Zusatzmaterialien für Präsentationen. Der Schwerpunkt liegt durchgängig auf Erkrankungen. Zielgruppe sind die vielen Physiologen und Entwicklungsbiologen, die zwar mit der Bedeutung und den Mechanismen der Hormonregulation vertraut sind, aber über unzureichendes Hintergrundwissen im Bereich Epigenetik verfügen.

About the author

Subhrangsu S. Mandal is currently Associate Professor at the Department of Chemistry and Biochemistry, at The University of Texas at Arlington, Texas. He received his PhD degree from the Indian Institute of Science, Bangalore, where he worked on chemical nucleases and cationic liposome-mediated gene delivery in the laboratory of Professor S. Bhattacharya. He joined the laboratory of Professor Linda J. Reha-Krantz as an Alberta Heritage Foundation for Medical Research (AHFMR) postdoctoral fellow in the University of Alberta, Canada. He later moved to the laboratory of Professor Danny Reinberg to research on eukaryotic transcription and gene regulation in human at the University of Medicine and Dentistry of New Jersey (UMDNJ)/Howard Hughes Medical Institute (HHMI). Prof. Mandal began his independent career at University of Texas at Arlington in 2005. Specifically he is investigating the function of Mixed Lineage Leukemia (MLL) family of histone methyl-transferases in gene activation, estrogen signalling, and tumorigenesis. In parallel, the Mandal laboratory is also developing novel gene targeted cancer therapy using mouse models.

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