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Chapters: historical overview; persistent toxic substances; pathways of exposure; a review of the Great Lakes (GL) human health literature; human health studies outside of the Great Lakes -- exposure to similar persistent toxic substances; limitations of human health studies; characterization of exposure and determination of the profiles and levels in human biologic tissues and fluids; identification of sensitive and specific human reproductive end points; determination of the short- and long-term risk(s) of adverse health effects in the children of exposed parents; and establishment of registries &/or surveillance cohorts in the GL. Illustrated.
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