The 26 revised full papers presented were carefully reviewed and selected from 69 submissions. The papers focus on virtual and enhanced environments, covering topics such as motor rehabilitation; neuroimaging in rehabilitation; virtual rehabilitation; clinical assessment; cognitive rehabilitation; communication and language; ambisonics and audio environments; haptic devices; sensory impairment; medical systems; input devices; sensors and actuators; multi-user systems for user interaction; computer access; virtual humans; balance, posture and mobility; communications aids; tools for architectural/CAD design; product design, testing and prototyping; training tools for rehabilitation; augmented reality applications; human factors; rehabilitation robotics.