We proudly present the proceedings of 2nd International Seminar on Translation Studies, Applied Linguistics, Literature and Cultural Studies 2020 (STRUKTURAL 2020). It focuses on how disruptive era influences participants field of researches, especially in Humanities and Social Studies. As we know, the world today is changing and the world we are facing now is the one where everything is connected. Not only are our PCs, our tablets, our hand phones, and other devices connected but everything that happens in societies is also now “connected”. Today, even a robbery incident in a small village has a possibility to make a city in another part of the world collapse. This butterfly effect of social change may also give a big impact in our understanding and our field of study of social sciences and humanities. More than 70 manuscripts were presented at this conference with around 41 of them selected to be published in proceedings. We hope by this conference, discussions on how research on humanities and social studies is possible in a disruptive era will give a perspective for the social and humanities studies development.