Translational Surgery

Adam E.M. Eltorai · Jeffrey A. Bakal · Paige C. Newell · Adena J. Osband

Mar 2023 · Elsevier

About this ebook

Translational Surgery covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. The reader will come to fully understand important concepts including case-control studies, prospective cohort studies, randomized trials, and reliability studies. Investigators will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in surgical research, and know what is needed for collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the translational research navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in surgery, allowing the reader to learn how to evaluate the quality of such studies. Thus, they will improve at measuring outcomes; making effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every surgeon or surgical researcher who has ever had a good clinical idea, but not the knowledge of how to test it.

• Focuses on translational research in Surgery, covering the principles of evidence-based medicine and applying those principles to the design of translational investigations
• Provides a practical, straightforward approach to help surgeons and researchers navigate challenging aspects of study design and implementation
• Details valuable discussions on the critical appraisal of published studies in Surgery, allowing the reader to effectively use all types of evidence for patient care

About the author

Adam E. M. Eltorai, MD, PhD completed his graduate studies in Biomedical Engineering and Biotechnology along with his medical degree from Brown University. His work has spanned the translational spectrum with a focus on medical technology innovation and development. Dr. Eltorai has published numerous articles and books.

Jeff Bakal PhD, P.Stat. is the Program Director for Provincial Research Data Services at Alberta Health Services which operates the Alberta Strategy for Patient Oriented Research (SPOR) data platform and Health Service Statistical & Analytics Methods teams. He has over 10 years of experience working with Health Services data and Randomized Clinical Trials. He completed his PhD jointly with the Department of Mathematics and Statistics and the School of Physical Health and Education at Queen's University. He has worked on the methodology and analysis of several international studies in business strategy, ophthalmology, cardiology, geriatric medicine and the analysis of kinematic data resulting in several peer reviewed articles and conference presentations. His current interests are in developing statistical methodology for time-to-event data and the development of classification tools to assist in patient decision making processes.

Paige Newell MD received her Bachelor of Arts in History of Art and Architecture from Harvard University, and subsequently received her Doctor of Medicine from Lewis Katz School of Medicine at Temple University. She started general surgery residency at Brigham and Women's Hospital in Boston, MA in 2018, and spent her two years of dedicated research time from June 2020 - June 2022 as the Vicky and Joseph Safra Cardiac Surgery Clinical Outcomes Research Fellow within the Division of Cardiac Surgery at Brigham and Women's Hospital and as a research fellow for the Center for Surgery and Public Health. Her research interests include socioeconomic disparities in cardiac surgery outcomes and barriers to access to high quality care. After completing general surgery residency she plans to complete a fellowship in cardiothoracic surgery.

Adena Osband, MD is a graduate of the University of Pennsylvania and New Jersey Medical School. She is currently a transplant surgeon and director of the living donor program at Rhode Island Hospital, with over 15 years in practice. She also holds the positions of associate professor of surgery and director of surgical intern education at the Warren Alpert Medical School of Brown University.