Animal Models of Neurological Conditions: A Reference Guide for Neuroscience Researchers and Trainees

Jacob Raber

nov 2025 · Academic Press

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Animal Models of Neurological Conditions informs about novel animal models and their unique strengths and limitations in the research of neurological conditions. It demonstrates the importance of animal models' abilities to replicate only aspects of a given neurological condition and highlights the value of these animal models in increasing human brain function in afflicted patients. This book, comprised of thirteen chapters discusses various animal models and research methods for mental health, neurodevelopmental disorders, addiction, age-related neurodegenerative conditions, and viruses affecting brain function. Although developed with neuroscience researchers and trainees involved in pre-clinical and clinical research in mind, neurologists and other treatment professionals caring for patients with neurological conditions will also find value in this detailed resource.This is an invaluable resource for neuroscience researchers, trainees, and healthcare professionals. - Focuses on modern animal models of neurological conditions - Reviews research methods to assist in delating, improving, and potentially curing those afflicted with neurological conditions - Increases understanding of novel animal models and animal models involving state-of-the-art analyses to improve brain function in those afflicted by neurological conditions

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Jacob Raber, PhD received his BS in Chemistry and MS in Pharmacochemistry from the Free University of Amsterdam, his PhD in Molecular Genetics and Virology from the Weizmann Institute of Science, and further training under Floyd Bloom at the Scripps Research Institute, La Jolla, and Lennart Mucke at the Gladstone Institutes and UCSF. In 2001 he was recruited to Oregon Health & Science University (OHSU) in Portland, Oregon and currently serves as a professor in the Departments of Behavioral Neuroscience, Neurology, Psychiatry, and Radiation Medicine, an affiliate scientist in the division of Neuroscience at the ONPRC, and a Courtesy Professor in the College of Pharmacy at Oregon State University. He was an Ellison Medical Foundation New Scholar in Aging from 2002-2006. Dr Raber’s research is devoted to characterizing effects of environmental and genetic factors on brain function, identifying of affected pathways, and developing treatments to antagonize detrimental effects.