¿Biosafety in Microbiological & Biomedical Labs.¿ quickly became the cornerstone of biosafety practice & policy upon first pub. in 1984. The info. is advisory in nature even though legislation & reg¿n., in some circumstances, have overtaken it & made compliance with the guidance mandatory. This rev. contains these add¿l. chap.: Occupat¿l. med. & immunization; Decontam. & sterilization; Lab. biosecurity & risk assess.; Biosafety Level 3 (Ag.) labs.; Agent summary state. for some ag. pathogens; & Biological toxins. Also, chapters on the principles & practices of biosafety & on risk assess. were expanded; all agent summary state. & append. were rev.; & efforts were made to harmonize recommend. with reg¿s. promulgated by other fed. agencies.