Optimizing the Management of Fertility in Women over 40

Dimitrios S. Nikolaou · David B. Seifer

Oct 2022 · Cambridge University Press

About this ebook

Reproductive aging is a natural and universal process. Women frequently overestimate the age at which a significant decline in fertility occurs as well as overestimate the success of assisted reproductive technologies to circumvent age-related infertility. Yet there is much that modern medicine can do to improve conception rates in women who delay childbearing and to manage subsequent pregnancies. This book offers guidance on winning strategies for maximizing the live-birth rate and limiting the risk for women trying to conceive later in life. It is intended to assist in navigating this challenging journey and lead to peace of mind that women have been seen, heard, and treated as individuals in the process. Written by leading experts addressing medical options of applying advanced reproductive technologies, psychological, nutritional, lifestyle, systematic approaches to optimizing fertility care for the most challenging demographic of women in a practical, clinically orientated, and most importantly, positive way.

About the author

Dimitrios Nikolaou is a clinician sub-specialist and educator with long experience in the management of fertility in women over 40. He leads the Reproductive Ageing and Fertility Program at Chelsea and Westminster Hospital in London, UK, and the school of Reproductive Medicine, including the sub-specialty training program. He is a champion for patient support and the development of organizational systems to optimize patient experience. He introduced 'Early ovarian ageing' and has lectured internationally, contributing to a re-thinking of the concept of family planning as fertility-planning. He convened the 56th RCOG working group on Reproductive ageing and co-edited the accompanying book. He is the founder of 'fertility for life'.

David B. Seifer, MD is a board-certified reproductive endocrinologist at Yale Medicine Fertility Center in Orange, CT and is a Professor of Obstetrics, Gynecology and Reproductive Sciences at Yale School of Medicine and Fellowship Director of the Yale Reproductive Endocrinology and Infertility fellowship. Dr. Seifer has 30 years of clinical experience in reproductive endocrinology and infertility and is a past president of the Society for Assisted Reproductive Technology (SART), the primary national organization that sets clinical and laboratory guidelines and standards for safety and quality metrics for IVF in the United States. He has served as Co-Editor in- Chief of Reproductive Biology and Endocrinology since 2016 and has been actively conducting clinical and translational research with anti-mullerian hormone (AMH) as a marker of ovarian reserve for several decades.