High-Resolution NMR Techniques in Organic Chemistry

T. Claridge

Δεκ 1999 · Elsevier

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From the initial observation of proton magnetic resonance in water and in paraffin, the discipline of nuclear magnetic resonance has seen unparalleled growth as an analytical method. Modern NMR spectroscopy is a highly developed, yet still evolving, subject which finds application in chemistry, biology, medicine, materials science and geology.In this book, emphasis is on the more recently developed methods of solution-state NMR applicable to chemical research, which are chosen for their wide applicability and robustness. These have, in many cases, already become established techniques in NMR laboratories, in both academic and industrial establishments. A considerable amount of information and guidance is given on the implementation and execution of the techniques described in this book.

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Dr. Tim Claridge graduated in Chemistry and Analytical Science from Loughborough University of Technology in 1988, having also spent an industrial year at, what was then, Beecham Pharmaceuticals. This period germinated his early interest in NMR spectroscopy as an analytical and structural tool, and subsequently led to the completion of a D.Phil at the University of Oxford with the late Andrew Derome. Since 1992 he has been the NMR Facility Manager in the Dyson Perrins Laboratory at Oxford where his interests focus on the application of solution-state NMR techniques to address problems of structure and mechanism in a wide variety of chemical and biochemical systems. He currently serves on the committee of the UK Royal Society of Chemistry NMR Discussion Group.