Topics covered in Long Acting Injections and Implants include the historical development of the field, drugs, diseases and clinical applications for long acting injections and implants, anatomy and physiology for these systems, specific injectable technologies (including lipophilic solutions, aqueous suspensions, microspheres, liposomes, in situ forming depots and self-assembling lipid formulations), specific implantable technologies (including osmotic implants, drug eluting stents and microfabricated systems), peptide, protein and vaccine delivery, sterilization, drug release testing and regulatory aspects of long acting injections and implants.
This volume provides essential information for experienced development professionals but was also written to be useful for scientists just beginning work in the field and for others who need an understanding of long acting injections and implants. This book will also be ideal as a graduate textbook.
Dr. Jeremy Wright is a Principal Engineer at the DURECT Corporation in Cupertino, California. He has over 30 years of experience in the development of drug delivery systems. He has been a key contributor to the development of implantable osmotic systems for veterinary and human use (DUROS®) and is currently involved in research and development of injectable depot systems. Dr. Wright is the inventor on over 50 patents.
Dr. Diane J. Burgess is Distinguished Professor of Pharmaceutics, at the University of Connecticut. Her research efforts focus on gene and drug delivery and she has over 140 refereed publications. Dr. Burgess was the 2010 President of the Controlled Release Society (CRS), the 2002 President of the American Association of Pharmaceutical Scientists (AAPS) and is a CRS, AAPS and an American Institute for Medical and Biological Engineering (AIMBE) fellow. She is editor of the International Journal of Pharmaceutics.
The pharmaceutical scientist is faced with many challenges when innovating new products in this demanding field of controlled release. This book provides the reader with a comprehensive guide on the theories, applications, and challenges associated with the design and development of long acting veterinary formulations. The authoritative chapters of the book are written by some of the leading experts in the field. The book covers a wide scope of areas including the market influences, preformulation, biopharmaceutics, in vitro drug release testing and specification setting to name but a few. It also provides a detailed overview of the major technological advances made in this area. As a result this book covers everything a formulation scientist in industry or academia, or a student needs to know about this unique drug delivery field to advance health, production and reproduction treatment options and benefits for animals worldwide.