Compendium of Organic Synthetic Methods

Compendium of Organic Synthetic Methods

Book 8
Sold by John Wiley & Sons
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More than a one-volume listing of synthetic methods, Compendium ofOrganic Synthetic Methods offers chemists a highly focused andselective look at several thousand functional grouptransformations. Used by more professionals than any comparablereference on the market, this valuable desktop resource providesquick access to the recipes of the newest, most useful reactionsand transformations. It also affords professionals an unparalleledopportunity to browse the vast body of recent literature for newreactions and transformations that may be of interest.

Featuring 1,200 more entries than its predecessor, Volume 8 coversfunctional group transformations and carbon-carbon bond formingreactions appearing in the literature from 1990 through 1992. Itpresents approximately 1,400 examples of published reactions forthe preparation of monofunctional compounds and approximately 1,640examples of reactions that prepare difunctional compounds withvarious functional groups. It also features 60 more reviews thanVolume 7.

As in all the previous Compendium volumes, the classificationschemes used allow for quick and easy reference and informationretrieval. Chemical transformations are classified first by thereacting functional group of the starting material and then by thefunctional group formed. The transformation, major reagents thateffect the transformation, yield percentage, and stereochemistryare all clearly shown. The Compendium also includes indices forboth monofunctional and difunctional compounds as an efficientmeans of guiding you to specific classes of transformations.

Compendium of Organic Synthetic Methods, Volume 8 providesprofessional chemists and students unparalleled access to thewealth of methods, reactions, and transformations in contemporaryorganic chemistry.
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About the author

MICHAEL B. SMITH is Professor of Chemistry in the Department of Chemistry at the University of Connecticut, at Storrs. His research interests focus on developing asymmetric reactions based on manipulating chiral, nonracemic lactams. This work is applied to the development of new synthetic methods and the synthesis of polycyclic alkaloids with antitumor or antiviral activity. He was responsible for developing a new reagent for determining the enantiomeric composition of alcohols and amines bearing a chiral center. Dr. Smith received his doctorate in organic chemistry from Purdue and a bachelor's degree in chemistry from Virginia Tech.
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Additional Information

John Wiley & Sons
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Published on
Sep 9, 2009
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Science / Chemistry / Organic
Science / Chemistry / Physical & Theoretical
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The new, revised and updated 7th edition ofMarch’s Advanced Organic Chemistry clearly explainsthe theories and examples of organic chemistry, providing the mostcomprehensive resource about organic chemistry available.

Readers are guided on planning and execution of multi-stepsynthetic reactions, with detailed descriptions of all thereactions. The first five chapters deal with the structure oforganic compounds and discuss important organic chemistrybonds, fundamental principles of conformation, and stereochemistryof organic molecules, and reactive intermediates in organicchemistry. Chapters 6 to 9 are concerned with generalprinciples of mechanism in organic chemistry, including acids andbases, photochemistry, sonochemistry and microwave irradiation, andfinally the relationship between structure and reactivity. Thelast 10 chapters cover the nature and the scope of organicreactions and their mechanisms.

The 7th edition proves again it is a must-havedesktop reference and textbook for every student and professionalworking in organic chemistry or related fields.

Key features of the 7th edition:

Every chapter has been updated with the most recent reactioninformation with references to both the primary and reviewliteratureNew to the 7th edition: 5,500 references since the lastedition, updates / rewrites of the retained sections, and anupdated index in Appendix BContains more than 1650 reactions and 20,000 valuablereferences to the primary literatureIncludes appendices on the literature of organic chemistry andthe classification of reactions according to the compoundssynthesizedGuides the reader on planning and execution of multi-stepsynthetic reactions, with detailed descriptions of all thereactions. 

Reviews of the previous edition:

"...a favorite general organic chemistry text and an easy-to-useone-volume reference. We are confident that this book will remain adominant reference and that it will reside on many chemists'personal bookshelves." –Journal of MedicinalChemistry

"Who can hope to be seriously accepted as a member of theorganic chemistry community without being in possession of at leastone edition of 'March'?" –Chemistry and Industry

Based on the premise that many, if not most, reactions in organic chemistry can be explained by variations of fundamental acid-base concepts, Organic Chemistry: An Acid–Base Approach provides a framework for understanding the subject that goes beyond mere memorization. The individual steps in many important mechanisms rely on acid–base reactions, and the ability to see these relationships makes understanding organic chemistry easier. Using several techniques to develop a relational understanding, this textbook helps students fully grasp the essential concepts at the root of organic chemistry.

Providing a practical learning experience with numerous opportunities for self-testing, the book contains:

Checklists of what students need to know before they begin to study a topic Checklists of concepts to be fully understood before moving to the next subject area Homework problems directly tied to each concept at the end of each chapter Embedded problems with answers throughout the material Experimental details and mechanisms for key reactions

The reactions and mechanisms contained in the book describe the most fundamental concepts that are used in industry, biological chemistry and biochemistry, molecular biology, and pharmacy. The concepts presented constitute the fundamental basis of life processes, making them critical to the study of medicine. Reflecting this emphasis, most chapters end with a brief section that describes biological applications for each concept. This text provides students with the skills to proceed to the next level of study, offering a fundamental understanding of acids and bases applied to organic transformations and organic molecules.

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