Microscopic Imaging Through Turbid Media: Monte Carlo Modeling and Applications

Min Gu · Xiaosong Gan · Xiaoyuan Deng

Apr. 2015 · Springer

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This book provides a systematic introduction to the principles of microscopic imaging through tissue-like turbid media in terms of Monte-Carlo simulation. It describes various gating mechanisms based on the physical differences between the un scattered and scattered photons and method for microscopic image reconstruction, using the concept of the effective point spread function. Imaging an object embedded in a turbid medium is a challenging problem in physics as well as in bio photonics. A turbid medium surrounding an object under inspection causes multiple scattering, which degrades the contrast, resolution and signal-to-noise ratio. Biological tissues are typically turbid media. Microscopic imaging through a tissue-like turbid medium can provide higher resolution than transillumination imaging in which no objective is used. This book serves as a valuable reference for engineers and scientists working on microscopy of tissue turbid media.

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Min Gu is Director of the Centre for Micro-Photonics at Swinburne University of Technology in Australia. He is an established researcher in the fields of nanophotonics and biophotonics, and has internationally renowned expertise in three-dimensional optical imaging theory. Professor Gu is a Fellow of the Australian Academy of Science and the Australian Academy of Technological Sciences and Engineering. He has published over 550 articles, along with two reference books in the field of optics.