Presenilins and Alzheimer’s Disease

Steven G. Younkin · Rudolph E. Tanzi

12/2012 · Springer Science & Business Media

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The role of the familial Alzheimer's Disease genes called "presenilins" in causing neuronal cell death and Alzheimer-related pathology.

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Rudolph E. Tanzi, Ph.D is a neurologist, noted for his work in identifying genes for neurological disease. He co-discovered all three genes that cause early-onset familial Alzheimer's Disease. His distinguished career includes Professor of Neurology and holder of the Joseph P. and Rose F. Kennedy Endowed Chair in Neurology at Harvard University, Vice-Chair of Neurology and Director of the Genetics and Aging Research Unit at Massachusetts General Hospital, and currently leads the Alzheimer's Genome Project. He has published numerous scientific papers and is working on new therapies for treating and preventing Alzheimer's Disease based on his genetic discoveries. He is co-author of the books Decoding Darkness: The Search for the Genetic Causes of Alzheimer's Disease, Super Brain: Unleashing the Explosive Power of Your Mind to Maximize Health, Happiness, and Spiritual Well-Being, and Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being. His latest book, co-authored with Deepak Chopra, is The Healing Self: A Revolutionary New Plan to Super Charge Your Immunity and Stay Well for Life.