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It is now established that the interplay between environmental exposure and molecular stress response pathways plays a critical role in skin health and disease, and a refined mechanistic understanding of this phenomenon at the molecular level promises to open new avenues for targeted therapeutic strategies that may benefit patients in the near future. Coauthored by recognized international leaders in molecular and clinical biomedical sciences, this novel book provides a comprehensive perspective on environmental exposure-induced skin stress response pathways. Focusing on molecular opportunities targeting skin stress response pathways that are involved in cutaneous barrier function and repair, antimicrobial defense, immune regulation, inflammation, and malignant progression, the book is essential reading for students, basic researchers, and biomedical health care professionals interested in skin health and disease with implications for small molecule therapeutic development.
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作者简介
As an Associate Professor, Pharmacology and Toxicology, College of Pharmacy, University of Arizona and President of the American Society for Photobiology (ASP; 2016-2018), Dr. Wondrak's research examines the pathological role of oxidative and proteotoxic stress in solar photodamage and skin cancer aiming at the design of novel molecular strategies for prevention and therapeutic intervention. http://www.pharmacy.arizona.edu/directory/georg-wondrak-phd
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