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The Chinese Academy of Sciences reports how the country is modernizing science and technology and social changes for a developed world expected to triple in population and economic size over the next five decades. Revolutions in S&T require changing from imitation to innovation, independence, and institutions. Breakthroughs are expected in information science that will outpace technology. Computational thinking combines man-cyber-physical in a ternary universe. The plan is to absorb global innovations and intellectual resources. The format is like a brochure that defines structure, characteristics, steps and research support.The text is supported by data formatted in tables, charts, and highlighted boxes which detail characteristic indicators. There are five chapters by a committee of five writers and forty reviewers representing over three-hundred members. It is written at the level of principles and categories rather than specifics like the design of a new plane, and compares the rate of modernization of twenty-four countries. The major topics are economics, emerging areas, security, basic science, sustainability, and strategic efforts. This will be followed up by actual research, publications, workshops, peer review and priorities. It refers to relevant past plans, the immediately previous of which lasted for four years. It adds integration between demonstration and application, e.g. the topic of social computing and how it goes from electronic to ubiquitous. By 2050, China sees itself as an open society, advanced in culture, ethics, politics, materials, and conservation. Eight basic and strategic systems for economic development include energy, materials and manufacturing, networking, agriculture and biology, health, ecological and environmental, space and ocean, and security. Three emerging cross-disciplinary areas are nanotech, space, and complex systems. Security recognizes open-source intelligence and has two areas, space situational awareness, and social computing and parallel management systems. Four basic science areas are dark matter and energy, controlling structure of matter, synthetic biology, and photosynthesis. Seven sustainability efforts are comprised by 4k meter transparence underground to see ore deposits, renewable energy, deep geothermal, nuclear, marine, stem cells and regenerative medicine, and early diagnosis and intervention of chronic diseases. Six strategic efforts are post-IP networking, green manufacturing, process engineering, ubiquitous sensing, exa supercomputing, and molecular design. The primary milestones are shown for the years 2020, 2030 and 2050.