How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research

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A complete guide to understanding cluster randomised trials

Written by two researchers with extensive experience in thefield, this book presents a complete guide to the design, analysisand reporting of cluster randomised trials. It spans a wide rangeof applications: trials in developing countries, trials in primarycare, trials in the health services. A key feature is the use of Rcode and code from other popular packages to plan and analysecluster trials, using data from actual trials.  The bookcontains clear technical descriptions of the models used, andconsiders in detail the ethics involved in such trials and theproblems in planning them. For readers and students who do notintend to run a trial but wish to be a critical reader of theliterature, there are sections on the CONSORT statement, andexercises in reading published trials.

  • Written in a clear, accessible style
  • Features real examples taken from the authors’ extensivepractitioner experience of designing and analysing clinicaltrials
  • Demonstrates the use of R, Stata and SPSS for statisticalanalysis
  • Includes computer code so the reader can replicate all theanalyses
  • Discusses neglected areas such as ethics and practical issuesin running cluster randomised trials

How to Design, Analyse and Report Cluster Randomised Trialsin Medicine and Health Related Research provides an excellentreference tool and can be read with profit by statisticians, healthservices researchers, systematic reviewers and critical readers ofcluster randomised trials.

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Additional Information

Publisher
John Wiley & Sons
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Published on
Mar 28, 2014
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Pages
272
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ISBN
9781118763605
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Language
English
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Genres
Mathematics / Probability & Statistics / Stochastic Processes
Medical / Clinical Medicine
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Content Protection
This content is DRM protected.
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Available on Android devices
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An authoritative resource that offers the statistical tools and software needed to design and plan valid clinical studies

Now in its fourth and extended edition, Sample Sizes for Clinical, Laboratory and Epidemiology Studiesincludes the sample size software (SSS) and formulae and numerical tables needed to design valid clinical studies. The text covers clinical as well as laboratory and epidemiology studies and contains the information needed to ensure a study will form a valid contribution to medical research.

The authors, noted experts in the field, explain step by step and explore the wide range of considerations necessary to assist investigational teams when deriving an appropriate sample size for their when planned study. The book contains sets of sample size tables with companion explanations and clear worked out examples based on real data. In addition, the text offers bibliography and references sections that are designed to be helpful with guidance on the principles discussed.

This revised fourth edition:

Offers the only text available to include sample size software for use in designing and planning clinical studiesPresents new and extended chapters with many additional and refreshed examplesIncludes clear explanations of the principles and methodologies involved with relevant practical examplesMakes clear a complex but vital topic that is designed to ensure valid methodology and publishable results Contains guidance from an internationally recognised team of medical statistics experts

Written for medical researchers from all specialities and medical statisticians, Sample Sizes for Clinical, Laboratory and EpidemiologyStudies offers an updated fourth edition of the important guide for designing and planning reliable and evidence based clinical studies.

An authoritative resource that offers the statistical tools and software needed to design and plan valid clinical studies

Now in its fourth and extended edition, Sample Sizes for Clinical, Laboratory and Epidemiology Studiesincludes the sample size software (SSS) and formulae and numerical tables needed to design valid clinical studies. The text covers clinical as well as laboratory and epidemiology studies and contains the information needed to ensure a study will form a valid contribution to medical research.

The authors, noted experts in the field, explain step by step and explore the wide range of considerations necessary to assist investigational teams when deriving an appropriate sample size for their when planned study. The book contains sets of sample size tables with companion explanations and clear worked out examples based on real data. In addition, the text offers bibliography and references sections that are designed to be helpful with guidance on the principles discussed.

This revised fourth edition:

Offers the only text available to include sample size software for use in designing and planning clinical studiesPresents new and extended chapters with many additional and refreshed examplesIncludes clear explanations of the principles and methodologies involved with relevant practical examplesMakes clear a complex but vital topic that is designed to ensure valid methodology and publishable results Contains guidance from an internationally recognised team of medical statistics experts

Written for medical researchers from all specialities and medical statisticians, Sample Sizes for Clinical, Laboratory and EpidemiologyStudies offers an updated fourth edition of the important guide for designing and planning reliable and evidence based clinical studies.

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