SignatureCare Emergency Center is a freestanding emergency room with locations in College Station, Preston, Midland, Frisco, Killeen, Odessa, and Texarkana, TX — with Bryan and Aggieland coming soon. The ER is open 24/7 and staffed with board-certified physicians and licensed nurses. The emergency rooms function like hospital ERs. SignatureCare's goal is to treat patients quickly and help them feel better as soon as possible. Find the nearest location, call directly, or get directions with just one tap — reaching us has never been easier.