关于此电子书
Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that selectively target this class of enzymes. Novel characteristics of PDEs are viewed as unique opportunities to increase specificity and selectivity when designing novel compounds for certain therapeutic indications. This chapter provides a summary of the major concepts related to the design and use of PDE inhibitors.
作者简介
STEFANO BASAGNI holds a PhD in computer science from the University of Milano, Italy, and a PhD in electrical engineering from the University of Texas at Dallas. He received his BSc degree in computer science from the University of Pisa, Italy, in 1991. Since January 2002, he has been an assistant professor of Computer Engineering in the Electrical and Computer Engineering Department of Northeastern University. MARCO CONTI received the Laurea degree in Computer Science from the University of Pisa, Italy. He is currently a senior researcher at the Informatics and Telematics Institute (IIT) of the Italian National Research Council (CNR). He served as program committee chair of IFIP-TC6 Conferences "Networking2002," and "PWC2003." He is on the editorial board of ACM Mobile Computing and Communications Review. SILVIA GIORDANO received her PhD from EPFL, Lausanne. She is currently coordinator of Wireless, Telecommunication and High Frequency at the University of Applied Science of Ticino (Switzerland), and working as scientific collaborator at IIT-CNR, Pisa (Italy). She is a technical editor of IEEE Communications Magazine. IVAN STOJMENOVIc received a PhD degree in mathematics from the University of Zagreb. He is currently full professor at the University of Ottawa (Canada). He is managing editor of the Journal of Multiple-Valued Logic and Soft Computing, and an editor of IEEE Transactions on Parallel and Distributed Systems, Parallel Processing Letters, and a few other journals. He recently edited the Handbook of Wireless Networks and Mobile Computing (Wiley, 2002).
为此电子书评分
欢迎向我们提供反馈意见。
如何阅读
智能手机和平板电脑
笔记本电脑和台式机
您可以使用计算机的网络浏览器聆听您在 Google Play 购买的有声读物。
电子阅读器和其他设备
如果要在 Kobo 电子阅读器等电子墨水屏设备上阅读，您需要下载一个文件，并将其传输到相应设备上。若要将文件传输到受支持的电子阅读器上，请按帮助中心内的详细说明操作。
